24. N. Momin, S. Pabel, A. Rudra, N. Kumowski, I.-H. Lee, K. Mentkowski, M. Yamazoe, L. Stengel, C. G. Muse, H. Seung, A. Paccalet, C. Gonzalez-Correa, E. Jacobs, J. Grune, M. J. Schloss, S. Sossalla, G. Wojtkiewicz, Y. Iwamoto, P. McMullen, R. N. Mitchell, P. T. Ellinor, D. G. Anderson, K. Naxerova, M. Nahrendorf, M. Hulsmans, Therapeutic Spp1 silencing in TREM2+ cardiac macrophages suppresses atrial fibrillation. bioRxiv, https://doi.org/10.1101/2024.08.10.607461. (2024).
23. N. Momin. Balancing safety and efficacy: tuning the biodistribution and pharmacokinetics of cytokine immunotherapies. Current Opinion in Biotechnology. 84 (2023). https://doi.org/10.1016/j.copbio.2023.102994. (IF = 10.3)
22. N. Momin, N. K. Mehta, N. R. Bennett, L. Ma, J. R. Palmeri, M. M. Chinn, E. A. Lutz, B. Kang, D. J. Irvine, S. Spranger, K. D. Wittrup. Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy. Science Translational Medicine. 11 (2019). https://doi.org/10.1126/scitranslmed.aaw2614. (IF = 17.2)
21. N. Momin, J. R. Palmeri, E. A. Lutz, N. Jailkhani, H. Mak, A. Tabet, M. M. Chinn, B. Kang, V. Spanoudaki, R. O. Hynes, K. D. Wittrup. Maximizing response to intratumoral immunotherapy in mice by tuning local retention. Nature Communications. 13, 109 (2022). https://doi.org/10.1038/s41467-021-27390-6. (IF = 14.9)
20. E. A. Lutz*, N. Jailkhani*, N. Momin*, Y. Huang, A. M. Sheen, B. Kang, R.O. Hynes, K. D. Wittrup. Intratumoral nanobody-IL-2 fusions that bind the tumor extracellular matrix suppress solid tumor growth in mice. PNAS Nexus. gac244 (2022). *co-first author; https://doi.org/10.1093/pnasnexus/pgac244.(IF = 12.8)
19. N. Momin, S. Lee, A. K. Gadok, D. J. Busch, G. D. Bachand, C. C. Hayden, J. C. Stachowiak, D. Y. Sasaki. Designing lipids for selective partitioning into liquid ordered membrane domains. Soft Matter. 11, 3241–3250 (2015). https://doi.org/10.1039/C4SM02856B. (IF = 4.1)
18. N. K. Mehta, K. Rakhra, K. A. Meetze, B. Li, N. Momin, J. Y. H. Chang, K. D. Wittrup, P. A. Baeuerle, J. S. Michaelson, CLN-617 retains IL2 and IL12 in injected tumors to drive robust and systemic immune-mediated antitumor activity. Cancer Immunology Research. 12, 1022–1038 (2024). https://doi.org/10.1158/2326-6066.CIR-23-0636. (IF = 8.1)
17. J. A. Stinson, M. M. P. Barbosa, A. Sheen, N. Momin, E. Fink, J. Hampel, K. Selting, R. Kamerer, K. L. Bailey, K. D. Wittrup, T. M. Fan, Tumor-localized interleukin-2 and interleukin-12 combine with radiation therapy to safely potentiate regression of advanced malignant melanoma in pet dogs, bioRxiv. (2024). https://doi.org/10.1101/2024.02.12.579965.
16. N. Hegemann, P. Sang, J. H. Kim, C. Koçana, N. Momin, J. Klages, M. M. Kucherenko, C. Knosalla, B. O’Brien, S. Simmons, M. Nahrendorf, W. M. Kuebler, J. Grune, Ultrasonographic assessment of pulmonary and central venous congestion in experimental heart failure. Am. J. Physiol. Heart Circ. Physiol. 326, H433–H440 (2024). https://doi.org/10.1152/ajpheart.00735.2023.(IF = 4.1)
15. J. A. Stinson*, A. Sheen*, N. Momin, J. Hampel, R. Bernstein, R. Kamerer, B. Fadl-Alla, J. Samuelson, E. Fink, T. M. Fan, K. D. Wittrup, Collagen-anchored interleukin-2 and interleukin-12 safely reprogram the tumor microenvironment in canine soft-tissue sarcomas. Clinical Cancer Research. 29, 2110–2122 (2023). *co-first author. https://doi.org/10.1158/1078-0432.CCR-23-0006.(IF = 10.4)
14. M. Hulsmans*, M. J. Schloss*, I.-H. Lee*, A. Bapat, Y. Iwamoto, C. Vinegoni, A. Paccalet, M. Yamazoe, J. Grune, S. Pabel, N. Momin, H. Seung, N. Kumowski, F. E. Pulous, D. Keller, C. Bening, U. Green, J. K. Lennerz, R. N. Mitchell, A. Lewis, B. Casadei, O. Iborra-Egea, A. Bayes-Genis, S. Sossalla, C. S. Ong, R. N. Pierson, J. C. Aster, D. Rohde, G. R. Wojtkiewicz, R. Weissleder, F. K. Swirski, G. Tellides, G. Tolis Jr, S. Melnitchouk, D. J. Milan, P. T. Ellinor, K. Naxerova, M. Nahrendorf, Recruited macrophages elicit atrial fibrillation. Science. 381, 231–239 (2023). *co-first author. https://doi.org/10.1126/science.abq3061. (IF = 44.7)
13. M. Zagorulya, L. Yim, D. M. Morgan, A. Edwards, E. Torres-Mejia, N. Momin, C. V. McCreery, I. L. Zamora, B. L. Horton, J. G. Fox, K. D. Wittrup, J. C. Love, S. Spranger, Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer. Immunity. 56, 386-405.e10 (2023). https://doi.org/10.1016/j.immuni.2023.01.010.(IF = 25.5)
12. B. L. Horton, A. D. D’Souza, M. Zagorulya, C. V. McCreery, G. C. Abhiraman, L. Picton, A. Sheen, Y. Agarwal, N. Momin, K. D. Wittrup, F. M. White, K. C. Garcia, S. Spranger, Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2. JCI Insight. 8 (2023). https://doi.org/10.1172/jci.insight.172728. (IF = 6.3)
11. E. A. Lutz, Y. Agarwal, N. Momin, S.C. Cowles, J.R. Palmeri, E. Duong, V. Hornet, A. Sheen, B.M. Lax, A.M. Rothschilds, D.J. Irvine, S. Spranger, K.D. Wittrup. Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies. Proc. Natl. Acad. Sci. U.S.A. 119 (2022). https://doi.org/10.1073/pnas.2205983119. (IF=11.2)
10. F. E. Pulous, J. C. Cruz-Hernández, C. Yang, Z. Kaya, A. Paccalet, G. Wojtkiewicz, D. Capen, D. Brown, J. W. Wu, M. J. Schloss, C. Vinegoni, D. Richter, M. Yamazoe, M. Hulsmans, N. Momin, J. Grune, D. Rohde, C. S. McAlpine, P. Panizzi, R. Weissleder, D. Kim, F. K. Swirski, C. P. Lin, M. A. Moskowitz, M. Nahrendorf. Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis. Nature Neuroscience. 25(5):567-576 (2022). https://doi.org/10.1038/s41593-022-01060-2. (IF = 24.8)
9. B. Horton, D. Morgan, N. Momin, M. Zagorulya, E. Torres-Mejia, V. Bhandarkar, K.D. Wittrup, C.J. Love, S. Spranger. Lack of CD8 + T cell effector differentiation during priming mediates checkpoint blockade resistance in non-small cell lung cancer. Science Immunology. 6(64):eabi8800 (2021). https://doi.org/10.1126/sciimmunol.abi8800. (IF = 13.4)
8. B.K. Kang, N. Momin, K. D. Moynihan, M. Silva, Y. Li, D.J. Irvine, K.D. Wittrup. Immunotherapy-induced antibodies to endogenous retroviral envelope glycoprotein confer tumor protection in mice. PLoS One. 16(4) e0248903. (2021). https://doi.org/10.1371/journal.pone.0248903. (IF = 3.2)
7. Y. Li, Z. Su, W. Zhao, X. Zhang, N. Momin, C. Zhang, K. D. Wittrup, Y. Dong, D. J. Irvine, R. Weiss. Multifunctional oncolytic nanoparticles carrying therapeutic self-replicating RNA eliminate established tumors and prime systemic immunity. Nature Cancer. (2020). https://doi.org/10.1038/s43018-020-0095-6. (IF = 53.1)
6. N. Mehta, R. Pradhan, A. Soleimany, K. D. Moynihan, A. M Rothschilds, N. Momin, K. Rakhra, J. Mata-Fink, S. Bhatia, K. D. Wittrup, D. J. Irvine. Pharmacokinetic tuning of protein-antigen fusions to enhance the potency of therapeutic T cell vaccines. Nature Biomedical Engineering. (2020). https://doi.org/10.1038/s41551-020-0563-4. (IF = 25.7)
5. Y. J. Xie, M. Dougan, J. R. Ingram, N. Pishesha, T. Fang, N. Momin, H. L. Ploegh. Improved Antitumor Efficacy of Chimeric Antigen Receptor T Cells that Secrete Single-Domain Antibody Fragments. Cancer Immunology Research. 8, 518–529 (2020). https://doi.org/10.1158/2326-6066.CIR-19-0734. (IF = 8.7)
4. D. Dréau, L. J. Moore, M. Wu, L. D. Roy, L. Dillion, T. Porter, R. Puri, N. Momin, K. D. Wittrup, P. Mukherjee. Combining the Specific Anti-MUC1 Antibody TAB004 and Lip-MSA-IL-2 Limits Pancreatic Cancer Progression in Immune Competent Murine Models of Pancreatic Ductal Adenocarcinoma. Frontiers in Oncology. 9, 330 (2019). https://doi.org/10.3389/fonc.2019.00330. (IF = 6.2)
3. Y.J. Xie, M. Dougan, N. Jailkhani, J. Ingram, T. Fang, L. Kummer, N. Momin, N. Pishesha, S. Rickelt, R.O. Hynes, H. Ploegh. Nanobody-based CAR T cells that target the tumor microenvironment inhibit the growth of solid tumors in immunocompetent mice. Proc. Natl. Acad. Sci. U.S.A. 116, 7624–7631 (2019). https://doi.org/10.1073/pnas.1817147116. (IF = 11.2)
2. B. H. Kwan, E. F. Zhu, A. Tzeng, H. R. Sugito, A. A. Eltahir, B. Ma, M. K. Delaney, P. A. Murphy, M. J. Kauke, A. Angelini, N. Momin, N. K. Mehta, A. M. Maragh, R. O. Hynes, G. Dranoff, J. R. Cochran, K. D. Wittrup. Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses. Journal of Experimental Medicine. 214, 1679–1690 (2017). https://doi.org/10.1084/jem.20160831. (IF = 14.3)
1. C. S. Scheve, P. A. Gonzales, N. Momin, J. C. Stachowiak. Steric pressure between membrane-bound proteins opposes lipid phase separation. Journal of the American Chemical Society. 135, 1185–1188 (2013). https://doi.org/10.1021/ja3099867. (IF = 11.4)